TORONTO -- Toronto FC will be without the heart of its defence as well as star striker Jermain Defoe and possibly midfielder Jonathan Osorio for Saturdays game in Columbus against the unbeaten Crew. Captain Steven Caldwell is suspended while fellow centre back Doneil Henry has been sidelined by a twisted knee suffered in last weekends 3-0 loss at Real Salt Lake City. Defoe, who has all three of Torontos goals this season, strained his left hamstring last week and was substituted in the 61st minute. "Not a major thing but definitely unavailable this weekend," Toronto manager Ryan Nelsen said earlier in the week. Osorio, who missed last weeks game with a hamstring injury, "probably wont make it as well," Nelsen said after practice Friday. It looks like rookie Nick Hagglund, a 21-year-old Cincinnati native, will start at centre back Saturday. He impressed during the pre-season when he was pressed into emergency action at right fullback due to injuries elsewhere on the roster. Gale Agbossoumonde, Bradley Orr and Ryan Richter can also play in the centre of defence. Left fulback Justin Morrow has also played at centre back but a hip injury to backup fullback Ashtone Morgan has taken away some of Nelsens flexibility at the back. Canadian Kyle Bekker may step in for Osorio in central midfield alongside American international Michael Bradley. Nelsen did not say who would wear the captains armband in Caldwells absence but it will likely be Bradley, coming off an impressive showing in Wednesdays 2-2 tie in Glendale, Ariz., between the U.S. and Mexico. Bradley scored one goal and set up another. Toronto and the Columbus Crew are both off to their best starts in MLS history. But Columbus (3-0-0) is unbeaten while Toronto (2-1-0) is coming off a loss and is hurting. Caldwell was suspended for one game and fined an undisclosed amount by the leagues disciplinary committee for a studs-up tackle on Real Salt Lake midfielder Ned Grabavoy last week. The Toronto skipper was yellow-carded on the play. "Very disappointed with my 1 match ban," Caldwell said via Twitter. "Never tackled to hurt someone in my life. Sorry I wont be out there Saturday to help the lads." Toronto will get Brazilian midfielder Jackson back from a one-game suspension for an elbow thrown off the ball in the win over D.C. United. And Brazilian goalkeeper Julio Cesar has recovered from a knock to the knee from a goalmouth collision in Salt Lake. Toronto will have to watch Argentine attacker Federico Higuain, who has three goals (two from the penalty spot) and has been involved in five of the Crews seven goals this season. Columbus showed its resilience last week in Seattle when it won 2-1 on a 94th-minute goal by Justin Meram -- with an assist from Higuain -- that snapped the Sounders 51-match unbeaten run when they score the first goal. Toronto, meanwhile, got a reality check in a 3-0 loss at Real Salt Lake City after opening the season with victories over Seattle and D.C. United. Nelsen says he is not surprised by Columbus fast start out of the gate. "Not at all. A lot of their players are good MLS players that have been around. Gregg (Berhalter) is a really good coach and hes got them going really good ... There hasnt been a hell of a lot of turnover there, especially in the main positions. Hes done really well." Berhalter took over as the Crews seventh head coach -- and first sporting director -- last November after two seasons at the helm of Swedish club Hammarby IF. As a player, the defender spent 18 seasons in the Netherlands, England, Germany and the U.S., winning 44 caps for the American national team. Toronto has New Zealand midfielder Tim Payne, currently on Blackburns books, in camp on trial. NOTES -- The Crew have lost to Toronto FC just twice in 19 meetings all-time and lead the Trillium Cup rivalry (10-2-7). Columbus is 7-1-2 against Toronto at home. Torontos 2-1 home win over the Crew last July was the first since a 4-2 victory in September 2011 in Columbus, which ended a 12-game TFC winless run against Columbus ... Crew defensive midfielder Tony Tchani played 12 games for Toronto in 2011 before being traded to Columbus for Andy Iro and Leandre Griffit. Kanken Backpack Mini Cheap . As each game passes (each has played close with the exception of last night) it becomes clearer just how evenly matched these two teams are and how one mistake, or one bad inning, is likely to sway the result. Fjallraven Kanken Uk . So what happens? Stevenson lands a huge left to Dawsons temple only 76 seconds into the opening round and walks away with the championship belt. "I said Id knock him out," said Stevenson (21-1). http://www.kankenbackpackuk.com/. MLB.com reported that the Dodgers locked the left-hander in for one year at $10 million with up to $4 million in incentives. Fjallraven Kanken Uk Cheap . Coach Randy Carlyle didnt know the severity of Bozaks injury. Bozak left the bench and went down the tunnel early in the second period, returned to play a handful of shifts and then did play in the third. Kanken Classic Backpack Sale . After a 10-game skid, winning sure feels good. Atlantas third error in the last two innings allowed Jackie Bradley Jr.Hibernian boss Alan Stubbs says promotion to the Premiership is the top priority, despite his club looking to end a 114-year wait for Scottish Cup glory. The Easter Road side take on Dundee United in the first cup semi-final on a newly-laid Hampden pitch this Saturday - live on Sky Sports - 24 hours before Celtic face Glasgow rivals Rangers in the other semi.The playing surface at Scotlands national stadium has been relaid since the Petrofac Training Cup final last weekend but Stubbs insists his side will have no trouble adapting to the new pitch. Speaking to Sky Sports News HQ, the former Everton and Celtic defender said: It looks fine. It looks good and it appears to have knitted together in a short space of time.But Im probably glad we are going to be the first ones to use it.Hibs beat their Premier League rivals 3-0 in the quarter-finals of the League Cup in November, but Stubbs says the result will have no bearing on the outcome this weekend. Why itll be a case of friends reunited when Hibernian face Dundee United in the Scottish Cup semi-final We will be motivated for this game.dddddddddddd You only have to look at where the game is being played, which is obviously very different (from last year), he said.But I honestly believe that Dundee United are stronger since the last time we played so when you put them into the mix, we are going to have a difficult game on Saturday.Our motivation is getting to a final and what we will be focused on is beating the team in front of us, who are trying to stop us getting to another final.A drop off in form has seen Hibs take maximum points from just two of their last 11 matches, but Stubbs is adamant promotion to the Premiership alongside Rangers is his ultimate goal. Falkirks Bob McHugh (19) celebrates his last-minute equaliser at Easter Road There is always a reason when you lose and we have contributed to that ourselves by making a couple of silly mistakes. But we need to get back to the very good form that we were in early on in the season, he added.Tuesday (a 2-2 draw with Falkirk) was the best performance we have put in for a while but we shot ourselves in the foot late on. But I have total belief in the players and I know we will turn our form around and I have no problem with that whatsoever.The priority has always been promotion but this match is the priority this weekend. All games are priorities, but we want to get up and that is our main focus and it has been all season. Nothing has changed but this is a game we are desperate to win. Also See: Falkirk hold Hibs Hibs fixtures Hibs stats Scottish Champ table ' ' '